Find Studio

Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry which is an analytical technique that measures the mass-to-charge ratio of charged particles.

pFind Studio is a computational solution for such mass spectrometry-based proteomics. It germinated in 2002 in Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China. We call ourselves "pFinders". Our goal is to study bioinformatics algorithms and to develop easy-to-use software tools to help answer biological questions.
pFind团队招收2020年度入学学生!The pFind team is recruiting new members for 2020!

What's New

July 30, 2019 - Our paper "A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides" has been accepted for publication by the Nature Communications.Congratulations!


July 22-26, 2019 - Associate Professor Hao Chi attended the annual international conference on Intelligent Systems for Molecular Biology (ISMB) 2019.

July 24, 2019 - Our paper "pValid: Validation Beyond the Target-Decoy Approach for Peptide Identification in Shotgun Proteomics" has been accepted for publication by the Journal of Proteome Research.


Software

pFind is a search engine for peptide and protein identification via tandem mass spectrometry.[download...]




pLink is a tool dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry.
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pNovo+ is a de novo peptide sequencing algorithm using complementary HCD and ETD tandem mass spectra. [download...]

Benchmark

We participated in the ABRF iPRG study with pFind developed by our group in the past few years.



"The mission of the ABRF iPRG (formerly the Bioinformatics Committee) is to educate ABRF members and the scientific community on best application and practice of bioinformatics toward accurate and comprehensive analysis of proteomics data."


We believe it is advantageous to improve our algorithms, software tools and strategies for proteome informatics.